About the study

ADDITION-DK includes randomised studies comparing routine treatment with more intensive treatment and cohort follow-up studies, and a total of 175 practices from five Danish regions participate in the study.

All 163,189 patients aged 40-69 years listed with these practices were invited to take part in a stepwise screening programme for diabetes. The first step was to complete a score questionnaire. People with a high screening score (indicating increased risk of type 2 diabetes) were requested to consult their general practitioner. Almost 28,000 people consulted their general practitioner and had blood samples taken.

Risk groups identified:

  •  2,463 persons with high risk of developing diabetes, i.e. impaired fasting glucose (IFG) and impaired glucose tolerance (IGF), (enrolled in ADDITION-PRO)
  • 6,944 persons without dysglycemia but at increased risk of cardiovascular disease according to the European Heart SCORE  5 (European Heart Journal (2003) 24, 987–1003) and
  • 1,533 persons with screen detected type 2 diabetes (enrolled in the ADDITION-EUROPE).